stem cell therapy for alzheimer's disease

Alzheimer’s is a devastating form of dementia which progressively worsens over time and has no cure. Harnessing the powerful healing properties of adult stem cells found in your own fat tissue, Okyanos Cell Therapy offers new hope for this neurodegenerative condition by enabling brain and nerve cell repair for the chance at an improved quality of life.

What is Alzheimer’s Disease?

Alzheimer’s Disease (AD) is a common neurological disorder which affects millions of people throughout the world. Although its exact cause is not known, researchers have seen environmental and lifestyle factors as well as genetics playing a role in the formation of AD. Plaque and toxin deposits in the brain cause once-healthy neurons (nerve cells) to work less efficiently together and, eventually, die. As this damage spreads to key parts of the brain, memories and cognitive function become drastically impaired while the brain itself actually begins to shrink in size.

Because AD is a progressive disorder, symptoms develop and worsen over time. Many with AD suffer from memory dysfunction, confusion and inability to learn, and some can develop psychotic symptoms such as hallucination and paranoia. The later stages of Alzheimer’s may bring about such severe brain tissue damage that the body begins to shut down.

Treating Multiple Underlying Factors of AD

The unique blend of stem and regenerative cells found in your adipose tissue have the capability to reduce inflammation and prevent continued cell death while repairing/replacing damaged tissue. These special healing cells also hold as their primary mechanism the growth of new blood vessels which restores the flow of oxygen-rich blood to the brain for a wide spectrum of healing benefits.

Doctors at Okyanos utilize a specifically developed protocol for opening up the blood brain barrier to help deliver stem cells directly to the brain; a technique that has been proven effective in independent studies. This enables the doctors to target your stem cells inside the brain to re-establish blood flow and repair damaged nerve cells (neurons).

Stem Cell Therapy for Alzheimer’s Disease: The Procedure

Stem cell treatment at Okyanos is a minimally invasive, same-day outpatient procedure. Though recovery can and does vary from patient to patient, our protocols are designed and carried out with the goal of keeping “downtime” to a minimum. A general overview of the procedure is as follows:

  1. First, water-assisted fat harvesting is done to obtain about a cup of adipose (fat) tissue.
  2. The unique blend of stem and regenerative cells which exist in the adipose tissue are then isolated and prepared for intravenous delivery utilizing an EU-approved, closed/sterile, fully automated CGMP cell processing system. For patients receiving direct injections, a closed/sterile, manually operated cell processing technology will be used to obtain a micro-fragmented, cell-rich product for injection.
  3. Approximately 45 minutes before stem and regenerative cell implantation begins, mannitol is administered to facilitate the cells crossing the blood brain barrier for a potentially more efficacious cell delivery.
  4. In accordance with the individualized treatment plan prepared for each patient, adult stem and regenerative cells are then delivered intravenously and (where appropriate) by direct injection. This combination of IV and direct injection is a standard technique developed by doctors at Okyanos. Direct injections are performed under ultrasound or 2D-fluoroscopic guidance to ensure proper placement of the cells.

To learn more about Okyanos Cell Therapy for neurologic or neurodegenerative conditions, contact a Patient Liaison to request a free educational consultation or dial 855-OKYANOS (855-659-2667).

References

Fat Tissue: An Underappreciated Source of Stem Cells for Biotechnology (April, 2006) in Trends in Biotechnology. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16488036.

Specific Induction of Neuronal Cells from Bone Marrow Stromal Cells and Application for Autologous Transplantation (June, 2004) in Journal of Clinical Investigation. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/15199405?dopt=Abstract&holding=f1000,f1000m,isrctn

Human Adipose Tissue-Derived Mesenchymal Stem Cells Secrete Functional Neprilysin-Bound Exosomes (February, 2013) in Scientific Reports. Retrieved from http://www.nature.com/srep/2013/130201/srep01197/full/srep01197.html

Alzheimer’s Disease Fact Sheet (September, 2012) from the National Institute on Aging. Retrieved from http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-fact-sheet.

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